What is Amyloidosis

Amyloidosis is a condition characterized by the deposition of abnormal proteins in various organs of the body including the heart. There are a few known causes, but there are predominantly two types:

  1. AL (Light Chain) Amyloidosis is caused by a disorder of bone marrow cells (plasma cells) that is associated with multiple myeloma.
  2. Transthryretin Amyloidosis (ATTR) is related to an overproduction of the TTR (Transports Thyroxine and Retinol) protein produced by the liver. ATTR can be a hereditary condition, and family members often need to be screened to ensure they do not share the responsible gene.

These types of Amyloidosis have different treatments and our Cardio-Oncology providers are trained in making the diagnosis and helping to determine the appropriate treatment regimen.

Patient information


Washington University and Barnes-Jewish Heart & Vascular Center
Center for Advanced Medicine
Washington University Medical Center
4921 Parkview Place Suite 8A
St. Louis, MO 63110
Phone: 314-362-1291

Heart & Vascular Center in South County
5201 Midamerica Plaza, Suite 2300
St. Louis, MO 63129
Phone: 314-362-1291

Heart & Vascular Center in West County
1020 North Mason, Suite 100
St. Louis, MO 63141
Phone: 314-362-1291

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Referring Physicians: 314-362-1291

Patients (please identify yourself as a cancer patient and specify if an urgent clinic visit is needed): 314-362-1291 or 888-210-8375