• ACE-MOVE:  Registry focusing on diagnosis and innovative treatments to improve outcomes in patients with amyloidosis.  Joshua Mitchell, MD.   Washington University.
  • AG10 OLE:  An open-label extension and safety monitoring study of acoramidis in participants with symptomatic transthyretin amyloid cardiomyopathy who completed the phase 3 ATTRIBUTE-CM trail.  Joshua Mitchell, MD.  Eidos Therapeutics.
  • APOLLO-B:  Phase 3 study evaluating the efficacy and safety of Patisiran in patients with transthyretin amyloidosis with cardiomyopathy.  Joshua Mitchell, MD.  Alnylam Pharmaceuticals.
  • ATRIUM:  Phase 3 study evaluating the efficacy and safety of Abatacept in hospitalized participants with Immune checkpoint inhibitor associated myocarditis.  Joshua Mitchell, MD.  Massachusetts General Brigham/Bristol Myers Squibb. 
  • ATTRIBUTE-CM:  Phase 3 study on the efficacy and safety of AG10 in subjects with symptomatic transthyretin amyloid cardiomyopathy.  Joshua Mitchell, MD.  Eidos Therapeutics.
  • BIOMARKER ANALYSIS IN PATIENTS WITH CANCER:  Prediction of cancer therapeutics related cardiac dysfunction and major adverse cardiovascular events in cancer patients treated with potentially cardiotoxic agents.  Joshua Mitchell, MD.  Washington University.
  • CARDIAC REHAB:  Cardiac Rehabilitation for patients receiving radiation therapy for thoracic cancers.  Shahed Badiyan, MD.  The Foundation for Barnes Jewish Hospital.
  • CARDIOTTRANSFORM:  Phase 3 study evaluating the efficacy and safety of ION-682884 in patients with transthyretin-mediated amyloid cardiomyopathy (ATTR-CM).  Joshua Mitchell, MD.  Ionis pharmaceuticals, Inc.
  • CARISMA:  Phase 2 study evaluating tyrosine kinase inhibitor risk-reduction with intensive systolic BP management.  Joshua Mitchell, MD.  ECOG-ACRIN Cancer Research Group.
  • CARING:  Continuous versus intermittent cardiac electrical monitoring in patients with acute promyelocytic leukemia or solid tumor cancer being treated with arsenic trioxide or capecitabine.  Joshua Mitchell, MD.  Washington University.
  • CLARITY:  A study of patients with histologically confirmed, advanced non-small cell lung cancer receiving radiation therapy evaluating biomarkers of cardiovascular stress, inflammation and vascular dysfunction.  Joshua Mitchell, MD.  National Heart, Lung and Blood Institute.
  • ICI ASSOCIATED MYOCARDITIS:  Characterization of heart tissue from patients with immune checkpoint inhibitor-associated myocarditis.  Jesus Jimenez, MD, Ph.D.  Washington University.
  • PATISIRAN EXPANDED ACCESS:  Expanded access protocol to provide patisiran to patients with transthyretin-mediated amyloidosis with cardiomyopathy. Joshua Mitchell, MD. Alnylam Pharmaceuticals, Inc.
  • PROACT:  Evaluation of MyoStrain® sequences with cardiac MRI to assist in the early detection and management of cardiotoxicity from therapeutics used to treat cancer.  Joshua Mitchell, MD.  Myocardial Solutions, Inc.
  • SURVIVE Registry: Cardiovascular toxicity in cancer and improvement in recovery registry.  Joshua Mitchell, MD
  • TACTIC:  A study of patients with HER-2 positive breast cancer receiving HER-2 directed therapy evaluating the timing of carvedilol initiation as an agent to reduce the incidence of LVEF decline.  Joshua Mitchell, MD.  Mayo Clinic
  • Transcutaneous Pacing (TCP) Pilot Study – EP Lab. Marye Gleva MD. Washington University
  • RESTART Study: Re-Ablation Using a Tailored Approach Targeting EGM-Dispersion in Afib patients. Daniel Cooper MD. Washington University
  • LIBREXIA-AF: A Phase 3, Randomized, Double-Blind, Double-Dummy, Parallel Group, Active-Controlled Study to Evaluate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor, Versus Apixaban in Participants with Atrial Fibrillation. Marye Gleva MD. Washington University
  • VIBRANT-AF: Volunteers to Investigate Best Results for Ablation and Novel Therapies for Atrial Fibrillation. Daniel Cooper MD. Washington University