News

Institute for Public Health names new director of the Global Health Center

The Institute for Public Health announces the appointment of Victor G. Dávila-Román, MD, as director of its Global Health Center. He was also named vice chair of global health in the Department of Medicine at the School of Medicine. Dávila-Román is professor of medicine in the cardiovascular division of the Department of Medicine, and a professor of anesthesiology and radiology at the School of Medicine. He earned his medical degree from the University of Puerto Rico, and has been affiliated with Washington University since 1986.

Radiation therapy reprograms heart muscle cells to younger state

New research from Washington University School of Medicine in St. Louis suggests that radiation therapy can reprogram heart muscle cells to what appears to be a younger state, fixing electrical problems that cause a life-threatening arrhythmia without the need for a long-used, invasive procedure.

Research to explore how genes, other factors affect cardiometabolic disease risk

Researchers at Washington University School of Medicine in St. Louis have received a four-year, $8.8 million grant to ramp up research aimed at unraveling how an individual’s risks of cardiometabolic diseases, such as heart disease and Type 2 diabetes, are influenced by the interaction of specific genes with demographic and lifestyle factors.

Prabhu named cardiovascular division director

Sumanth D. Prabhu, MD, an internationally recognized expert in how immunity and inflammation contribute to heart failure, has been named director of the Cardiovascular Division in the Department of Medicine at Washington University School of Medicine in St. Louis. He also will become cardiologist-in-chief at Barnes-Jewish Hospital and the Tobias and Hortense Lewin Distinguished Professor of Cardiovascular Diseases at the School of Medicine when his appointment begins Sept. 1.

Hammond receives Merck research fellowship

J. Gmerice Hammond, MD, a cardiologist and health policy research fellow in the Cardiovascular Division at Washington University School of Medicine in St. Louis, has received a Merck Fellowship Research Award from the Association of Black Cardiologists and the American College of Cardiology.

Scientists find genetic link to clogged arteries

High cholesterol is the most commonly understood cause of atherosclerosis, a hardening of the arteries that raises the risk of heart attack and stroke. But now, scientists at Washington University School of Medicine in St. Louis have identified a gene that likely plays a causal role in coronary artery disease independent of cholesterol levels. The gene also likely has roles in related cardiovascular diseases, including high blood pressure and diabetes.

COVID-19 can kill heart muscle cells, interfere with contraction

Since early in the pandemic, COVID-19 has been associated with heart problems, including reduced ability to pump blood and abnormal heart rhythms. But it’s been an open question whether these problems are caused by the virus infecting the heart, or an inflammatory response to viral infection elsewhere in the body. Such details have implications for understanding how best to treat coronavirus infections that affect the heart.

Immune therapies for heart disease aim of international research network

When a patient arrives in the emergency room with symptoms of a heart attack, doctors’ first priority is to restore blood flow to the heart muscle. Over the past few decades, therapeutic advances aimed at getting blood flowing and reducing strain on the heart have improved patients’ chances of surviving heart attacks to more than 90% from 50%.

Leadership Announcement – DOM Vice Chair for Health Equity

It is my pleasure to announce that Angela L. Brown, MD, Professor of Medicine, Division of Cardiology in the Department of Medicine at Washington University School of Medicine has been appointed as Vice Chair for Health Equity for the Department of Medicine. In this new role, Dr. Brown will lead our diversity, equity, inclusion and antiracism activities.

Maddox selected as American College of Cardiology trustee

Thomas M. Maddox, MD, a cardiologist and professor of medicine at Washington University School of Medicine in St. Louis, has been selected to serve as a trustee of the American College of Cardiology, an international professional society for cardiovascular care providers. He will serve a three-year term on the board of trustees beginning in April.

$10 million in grants aimed at preventing organ rejection after transplantation

Transplant surgeons and researchers at Washington University School of Medicine in St. Louis have received two grants totaling $10 million from the National Institutes of Health (NIH) to study how immune cells contribute to organ rejection, with the aim of improving the viability of organs after transplant.

Immune cells play surprising role in heart, mouse study suggests

New research in mice suggests that certain immune cells may help guide fetal development of the heart and play a role in how the adult heart beats, according to new research at Washington University School of Medicine in St. Louis.

High-protein diets boost artery-clogging plaque, mouse study shows

High-protein diets may help people lose weight and build muscle, but a new study in mice suggests they have a down side: They lead to more plaque in the arteries. Further, the new research shows that high-protein diets spur unstable plaque — the kind most prone to rupturing and causing blocked arteries. More plaque buildup in the arteries, particularly if it’s unstable, increases the risk of heart attack.

Heart pump devices associated with serious complications in some patients shortly after heart stent procedure

In critically ill patients who require a heart pump to support blood circulation as part of stent procedures, specific heart pumps have been associated with serious complications, according to a new study led by cardiologists at Washington University School of Medicine in St. Louis.

New clues found to help protect heart from damage after heart attack

Studying mice, scientists have shown that boosting the activity of specific immune cells in the heart after a heart attack …

Safety-Net Hospitals Fare Better Under New Medicare Reimbursement Rules

New Medicare reimbursement rules provide some relief to safety-net hospitals, shifting the burden of financial penalties toward hospitals serving wealthier …

Obese Mouse Mothers Trigger Heart Problems in Offspring

A diet high in fats and sugars is known for its unhealthy effects on the heart. Scientists now have found …

Is Intermittent Fasting the Cure for Diabetes?

(CNN) Three men with Type 2 diabetes used “intermittent fasting” to reverse their dependence on insulin, according to a report …

Lowering hospitals’ Medicare costs proves difficult

A payment system that provides financial incentives for hospitals that reduce health-care costs for Medicare patients did not lower costs …

Scientists ID source of damaging inflammation after heart attack

Scientists have zeroed in on a culprit that spurs damaging inflammation in the heart following a heart attack. The guilty …

Study of smoking and genetics illuminates complexities of blood pressure

Analyzing the genetics and smoking habits of more than half a million people has shed new light on the complexities …

Deadly heart rhythm halted by noninvasive radiation therapy

Radiation therapy often is used to treat cancer patients. Now, doctors at Washington University School of Medicine in St. Louis …

Aggressive testing provides no benefit to patients in ER with chest pain

Patients who go to the emergency room (ER) with chest pain often receive unnecessary tests to evaluate whether they are …

Drug trial shows promise for deadly neurological disorder

Results of a small clinical trial show promise for treating a rare neurodegenerative condition that typically kills those afflicted before …

Type of sugar may treat atherosclerosis, mouse study shows

Researchers have long sought ways to harness the body’s immune system to treat disease, especially cancer. Now, scientists have found …

BJC, School of Medicine establish Health Systems Innovation Lab

Improving patients’ health while reducing costs has become a mantra in health care, but this requires new ways of thinking …

Genetic errors associated with heart health may guide drug development

One family with rare gene mutation gives clues to preventing heart attacks. Natural genetic changes can put some people at …

Study reveals ways to improve outcomes, reduce costs for common heart procedure

Hospitals can improve patient care and reduce costs associated with coronary angioplasty if cardiologists perform more of these procedures through …

Genetic error that increases risk of aortic rupture identified

A study led by Washington University School of Medicine in St. Louis, in collaboration with Brigham and Women’s Hospital in …

New Guidelines Open Competitive Sports to Some Athletes with Heart Conditions

New guidelines from the American Heart Association and the American College of Cardiology have loosened some restrictions placed on competitive …

Genetic Study Finds New Gene and Pathway that Prevent Heart Attacks

A new study of genetic data from more than 190,000 people has identified genes that, when altered in specific ways, …

Discovery of Atherosclerosis as “Alzheimer’s disease” of Blood Vessels

Researchers at Washington University have discovered a novel phenomenon that takes place during the formation of atherosclerosis, or the progressive …

Washington People: Angela L. Brown

Angela L. Brown, MD, grew up on her family’s farm in southern Arkansas. At the farm’s peak, the family and …

Dietary Nitrate Increases Muscle Speed and Power in Patients with Heart Failure

Washington University researchers have demonstrated that beetroot juice, which is rich in nitrate (NO3), can increase muscle function in heart …

Genetic Study Identifies Individuals Who Benefit Most From Statins

Researchers at Washington University have shown that a panel of genetic markers can identify individuals at increased risk for heart …

Multiple Rare Gene Mutations Associated With Increased Risk of Heart Attack

Research performed at Washington University and other leading biomedical research institutions found that multiple rare mutations in two genes increase …

New Treatment For Marfan’s Syndrome Shows Promise

An investigational treatment for Marfan’s syndrome is as effective as the standard therapy at slowing enlargment of the aorta, new …

Gene Mutations in NPC1L1, the Target of the Drug Ezetimibe, Found to Reduce Cholesterol and Protect Against Heart Attack

Researchers at Washington University have shown that mutations in the gene NPC1L1 are associated with lower cholesterol and about 50% …

The Heart’s Own Immune Cells Can Help It Heal

Researchers at Washington University have found the heart holds its own pool of immune cells capable of helping it heal …

New Experimental Drug Reduces Tissue Damage Following Myocardial Infarction and Minimizes the Risk of Bleeding

Researchers at Washington University and St. Louis based APT Therapeutics Inc., show that a novel drug known as APT102 significantly …

Regions of the Genome Once Mislabled as ‘Junk’ are Linked to Pathogenesis of Heart Failure

Dr. Jeanne Nerbonne and a team of Washington University researchers from the Center of Cardiovascular Research (CCR) reported results from …

Nanoparticles Treat Muscular Dystrophy in Mice

A team of researchers at Washington University School of Medicine in St. Louis have demonstrated a new approach to treating …

New Insights Into How Immune Cells Heal Injured Hearts

The immune system plays an important role in the heart’s response to injury. But until recently, conflicting data made it …

2nd Annual CV Research Day

The Cardiovascular Division held its Second Annual Cardiovascular Research Day on December 5, 2013. The event drew more than 150 …

New Study from Washington University Investigators Shows that Black Patients Undergo Aortic Valve Replacement Less Frequently

In a study, published online in the American Journal of Cardiology, Drs. Michael Yeung (Division of Cardiology, University of North Carolina, …

Dr. Jeanne Nerbonne named as new Director of the Center for Cardiovascular Research

Jeanne M. Nerbonne, PhD, the Alumni Endowed Professor of Molecular Biology and Pharmacology, has been named director of the Center …

First Annual Cardiovascular Research Day

The Cardiovascular Division held its First Cardiovascular Research Day and Alumni Celebration on December 7, 2012. The event was the …

Over-Use of Drug-Eluting Stents Found

A review of more than 1.5 million percutaneous coronary intervention (PCI) procedures documented in the National Cardiovascular Data Registry has …

Noninvasive Imaging Technique May Help Kids with Heart Transplants

Washington University cardiologists have developed a noninvasive imaging technique that may help determine whether children who have had heart transplants …

Heart Disease and Diabetes

Researchers at Washington University School of Medicine have received a $4.7 million grant from the National Heart, Lung and Blood …