Drs. Richard Bach and Sharon Cresci of the Washington University Hypertrophic Cardiomyopathy Center of Excellence, along with collaborators, have published “Effect of Mavacamten in Women Compared With Men With Obstructive Hypertrophic Cardiomyopathy: Insights From EXPLORER-HCM” in the journal Circulation.
“Compared with men, women with hypertrophic cardiomyopathy (HCM) have a higher incidence of heart failure and worse outcomes. We investigated baseline clinical and echocardiographic characteristics and response to mavacamten among women compared with men in the EXPLORER-HCM study”, writes Cresci.
The study found similar outcomes in women compared with men in improvements in primary and secondary end points of the study, and greater overall improvements in health status for women enrolled.