Thomas M. Maddox, MD, SM

Thomas Maddox, MD, SM, is a cardiologist, physician executive, and clinical informatician focused on redesigning care delivery through digital transformation, artificial intelligence, and operational improvement. As Director of Clinical Innovation for the Department of Medicine at WashU Medicine, he leads efforts across WashU Medicine and Barnes-Jewish Hospital to use Epic, digital tools, predictive analytics, and AI to improve clinical workflows and patient care. His work emphasizes implementation and measurable operational impact, including improvements in hospital throughput, care transitions, clinical decision-making, patient safety, and clinician experience.

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Research Profile

Education

• BA, Economics/History: Rice University, Houston, Texas (1993)
• MD: Emory University, Atlanta, Georgia (1999)
• Residency: University of Texas Southwestern, Dallas, Texas (2002)
• Fellowship: Mount Sinai Medical Center, New York, New York (2006)
• MSc, Epidemiology: Harvard School of Public Health, Boston, Massachusetts (2007)

Board Certifications

• Cardiovascular Disease
• Clinical Informatics

Recognition

• Deputy Editor for Artificial Intelligence, Circulation
• President, Healthcare Innovators Professional Society
• Member, FDA Digital Health Advisory Committee
• Member, Digital Health Action Collaborative, National Academy of Medicine
• Member, Board of Trustees, American College of Cardiology (term completed 2026)

Clinical Interests

General cardiology, coronary artery disease, cardiovascular prevention, heart failure, and atrial fibrillation.

Research Interests

Healthcare delivery innovation; clinical informatics; digital transformation; artificial intelligence in health care; implementation of digital and AI-enabled tools into clinical workflows; operational redesign; learning health systems; cardiovascular quality, outcomes, and care delivery.