Electrophysiology

  • 3D MODEL:  Creation and validation of a 3D microphysiological disease model of human atrial conduction. Timothy Smith, DPhil., MD. Washington University.
    CURRENTLY ENROLLING
  • ACM IC14- Phase 1b to Evaluate the Safety, Pharmacokinetics and preliminary efficacy of Atibuclimab (IC14, Monoclonal Antibody Against CD14) in patients with Arrhythmogenic Cardiomyopathy. Phillip Cuculich, MD. Implicit Biosciences.
    CURRENTLY ENROLLING
  • BACKBEAT- BradycArdia paCemaKer with AV interval modulation for Blood prEssure treAtmenT. Daniel Cooper, MD. Orchestra Biomed. 
    CURRENTLY ENROLLING
  • CNCR REGISTRY:  A multi-center registry looking at patient outcomes for patients treated with cardiac radioablation. Pamela Samson, MD. Washington University. 
  • FACT-CRT:  Factors associated with response to cardiac resynchronization therapy in heart failure patients with non-LBBB ECG pattern. Marye Gleva, MD. University of Rochester.
    ENROLLMENT NEAR COMPLETION 
  • IVTCC:  A multicenter ventricular tachycardia catheter ablation registry. Daniel Cooper, MD. UCLA.
  • LEADR- Lead EvaluAtion for Defibrillation and Reliability, Prospective, multi-center, single-arm, non-randomized, Bayesian, adaptive study design, pre-market, interventional pivotal clinical study. Timothy Smith, MD. Medtronic.  
  • MECHANISTIC BASIS OF CARDIAC IRRADIATION:  Mechanistic basis of cardiac irradiation as a therapy for ventricular tachycardia. Stacey Rentschler, MD, PhD. Washington University.
  • LIBREXIA-AF: A Phase 3, Randomized, Double-Blind, Double-Dummy, Parallel Group, Active-Controlled Study to Evaluate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor, Versus Apixaban in Participants with Atrial Fibrillation. Marye Gleva MD. Washington University.
  • PAN:  Medtronic product surveillance registry. Mitchell Faddis, MD, Ph.D. Medtronic.
  • RADIATE-VT:  A study evaluating the safety and efficacy of cardiac radioablation compared to catheter ablation in patients with ventricular tachycardia. Daniel Cooper, MD. Varian Medical Systems. (pending)
  • REACT AF- Rhythm Evaluation for AntiCoagulaTion with Continuous Monitoring of Atrial Fibrillation. Thomas Maddox, MD. Federal Grant/Northwestern.
    CURRENTLY ENROLLING 
  • RESTART:  Re-ablation using a tailored approach targeting EGM-dispersion. Daniel Cooper, MD. Volta Medical.
  • RESTART Study: Re-Ablation Using a Tailored Approach Targeting EGM-Dispersion in Afib patients. Daniel Cooper MD. Washington University.
  • Transcutaneous Pacing (TCP) Pilot Study – EP Lab. Marye Gleva MD. Washington University.
  • VIBRANT-AF: Volunteers to Investigate Best Results for Ablation and Novel Therapies for Atrial Fibrillation. Daniel Cooper MD. Washington University.