Author: Kelly

A new study led by researchers at Washington University School of Medicine in St. Louis suggests that a widely used heart failure drug named sacubitril/valsartan is no better than valsartan alone in patients with severe heart failure. The study also provides evidence that the treatment with valsartan may be slightly safer for patients with advanced heart failure.

The Institute for Public Health announces the appointment of Victor G. Dávila-Román, MD, as director of its Global Health Center. He was also named vice chair of global health in the Department of Medicine at the School of Medicine. Dávila-Román is professor of medicine in the cardiovascular division of the Department of Medicine, and a professor of anesthesiology and radiology at the School of Medicine. He earned his medical degree from the University of Puerto Rico, and has been affiliated with Washington University since 1986.

New research from Washington University School of Medicine in St. Louis suggests that radiation therapy can reprogram heart muscle cells to what appears to be a younger state, fixing electrical problems that cause a life-threatening arrhythmia without the need for a long-used, invasive procedure.

Researchers at Washington University School of Medicine in St. Louis have received a four-year, $8.8 million grant to ramp up research aimed at unraveling how an individual’s risks of cardiometabolic diseases, such as heart disease and Type 2 diabetes, are influenced by the interaction of specific genes with demographic and lifestyle factors.

Sumanth D. Prabhu, MD, an internationally recognized expert in how immunity and inflammation contribute to heart failure, has been named director of the Cardiovascular Division in the Department of Medicine at Washington University School of Medicine in St. Louis. He also will become cardiologist-in-chief at Barnes-Jewish Hospital and the Tobias and Hortense Lewin Distinguished Professor of Cardiovascular Diseases at the School of Medicine when his appointment begins Sept. 1.

J. Gmerice Hammond, MD, a cardiologist and health policy research fellow in the Cardiovascular Division at Washington University School of Medicine in St. Louis, has received a Merck Fellowship Research Award from the Association of Black Cardiologists and the American College of Cardiology.

High cholesterol is the most commonly understood cause of atherosclerosis, a hardening of the arteries that raises the risk of heart attack and stroke. But now, scientists at Washington University School of Medicine in St. Louis have identified a gene that likely plays a causal role in coronary artery disease independent of cholesterol levels. The gene also likely has roles in related cardiovascular diseases, including high blood pressure and diabetes.

Since early in the pandemic, COVID-19 has been associated with heart problems, including reduced ability to pump blood and abnormal heart rhythms. But it’s been an open question whether these problems are caused by the virus infecting the heart, or an inflammatory response to viral infection elsewhere in the body. Such details have implications for understanding how best to treat coronavirus infections that affect the heart.

When a patient arrives in the emergency room with symptoms of a heart attack, doctors’ first priority is to restore blood flow to the heart muscle. Over the past few decades, therapeutic advances aimed at getting blood flowing and reducing strain on the heart have improved patients’ chances of surviving heart attacks to more than 90% from 50%.

It is my pleasure to announce that Angela L. Brown, MD, Professor of Medicine, Division of Cardiology in the Department of Medicine at Washington University School of Medicine has been appointed as Vice Chair for Health Equity for the Department of Medicine. In this new role, Dr. Brown will lead our diversity, equity, inclusion and antiracism activities.

Thomas M. Maddox, MD, a cardiologist and professor of medicine at Washington University School of Medicine in St. Louis, has been selected to serve as a trustee of the American College of Cardiology, an international professional society for cardiovascular care providers. He will serve a three-year term on the board of trustees beginning in April.

Transplant surgeons and researchers at Washington University School of Medicine in St. Louis have received two grants totaling $10 million from the National Institutes of Health (NIH) to study how immune cells contribute to organ rejection, with the aim of improving the viability of organs after transplant.

New research in mice suggests that certain immune cells may help guide fetal development of the heart and play a role in how the adult heart beats, according to new research at Washington University School of Medicine in St. Louis.

High-protein diets may help people lose weight and build muscle, but a new study in mice suggests they have a down side: They lead to more plaque in the arteries. Further, the new research shows that high-protein diets spur unstable plaque — the kind most prone to rupturing and causing blocked arteries. More plaque buildup in the arteries, particularly if it’s unstable, increases the risk of heart attack.