Leadership Announcement – DOM Vice Chair of Clinical Research (Links to an external site)

It is my pleasure to announce that Dr. Nancy K. Sweitzer, Professor of Medicine, has joined Washington University School of Medicine as the Vice Chair of Clinical Research for the Department of Medicine and Director of Clinical Research for the Division of Cardiology. Dr. Sweitzer joins us from the University of Arizona in Tucson, where she had been the Chief of Cardiovascular Medicine, Director of the Sarver Heart Center and Co-Director of the Clinical Translational Sciences Graduate Program for the University of Arizona Health Sciences.

Cardiovascular inflammation, heart failure focus of $6 million grant (Links to an external site)

Researchers at Washington University School of Medicine in St. Louis have received a $6 million grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health (NIH) to harness new understandings of the immune system to develop innovative therapies for heart failure and the prevention of organ rejection following heart transplantation.

Diabetes, metabolic syndrome in mice treated with novel class of compounds (Links to an external site)

A study in mice — led by researchers at Washington University School of Medicine in St. Louis — shows that a new class of compounds the scientists developed can improve multiple aspects of metabolic syndrome. An increasingly common group of conditions that often occur together, metabolic syndrome includes type 2 diabetes, high cholesterol, fat buildup in the liver, and excess body fat, especially around the waist. This syndrome often leads to cardiovascular disease, the leading cause of death worldwide.

Popular heart failure drug no better than older drug in sickest patients (Links to an external site)

A new study led by researchers at Washington University School of Medicine in St. Louis suggests that a widely used heart failure drug named sacubitril/valsartan is no better than valsartan alone in patients with severe heart failure. The study also provides evidence that the treatment with valsartan may be slightly safer for patients with advanced heart failure.

Institute for Public Health names new director of the Global Health Center (Links to an external site)

The Institute for Public Health announces the appointment of Victor G. Dávila-Román, MD, as director of its Global Health Center. He was also named vice chair of global health in the Department of Medicine at the School of Medicine. Dávila-Román is professor of medicine in the cardiovascular division of the Department of Medicine, and a professor of anesthesiology and radiology at the School of Medicine. He earned his medical degree from the University of Puerto Rico, and has been affiliated with Washington University since 1986.

Prabhu named cardiovascular division director (Links to an external site)

Sumanth D. Prabhu, MD, an internationally recognized expert in how immunity and inflammation contribute to heart failure, has been named director of the Cardiovascular Division in the Department of Medicine at Washington University School of Medicine in St. Louis. He also will become cardiologist-in-chief at Barnes-Jewish Hospital and the Tobias and Hortense Lewin Distinguished Professor of Cardiovascular Diseases at the School of Medicine when his appointment begins Sept. 1.

Hammond receives Merck research fellowship (Links to an external site)

J. Gmerice Hammond, MD, a cardiologist and health policy research fellow in the Cardiovascular Division at Washington University School of Medicine in St. Louis, has received a Merck Fellowship Research Award from the Association of Black Cardiologists and the American College of Cardiology.

Scientists find genetic link to clogged arteries (Links to an external site)

High cholesterol is the most commonly understood cause of atherosclerosis, a hardening of the arteries that raises the risk of heart attack and stroke. But now, scientists at Washington University School of Medicine in St. Louis have identified a gene that likely plays a causal role in coronary artery disease independent of cholesterol levels. The gene also likely has roles in related cardiovascular diseases, including high blood pressure and diabetes.

COVID-19 can kill heart muscle cells, interfere with contraction (Links to an external site)

Since early in the pandemic, COVID-19 has been associated with heart problems, including reduced ability to pump blood and abnormal heart rhythms. But it’s been an open question whether these problems are caused by the virus infecting the heart, or an inflammatory response to viral infection elsewhere in the body. Such details have implications for understanding how best to treat coronavirus infections that affect the heart.

Leadership Announcement – DOM Vice Chair for Health Equity (Links to an external site)

It is my pleasure to announce that Angela L. Brown, MD, Professor of Medicine, Division of Cardiology in the Department of Medicine at Washington University School of Medicine has been appointed as Vice Chair for Health Equity for the Department of Medicine. In this new role, Dr. Brown will lead our diversity, equity, inclusion and antiracism activities.

Maddox selected as American College of Cardiology trustee (Links to an external site)

Thomas M. Maddox, MD, a cardiologist and professor of medicine at Washington University School of Medicine in St. Louis, has been selected to serve as a trustee of the American College of Cardiology, an international professional society for cardiovascular care providers. He will serve a three-year term on the board of trustees beginning in April.

High-protein diets boost artery-clogging plaque, mouse study shows (Links to an external site)

High-protein diets may help people lose weight and build muscle, but a new study in mice suggests they have a down side: They lead to more plaque in the arteries. Further, the new research shows that high-protein diets spur unstable plaque — the kind most prone to rupturing and causing blocked arteries. More plaque buildup in the arteries, particularly if it’s unstable, increases the risk of heart attack.