Washington University - Cardiovascular Division

John P. Boineau, MD

Professor of Surgery, Medicine, and Biomedical Engineering
Co-Director, Cardiothoracic Surgery Research Laboratory
Co-Director, Nuclear Stress Lab, Barnes-Jewish Hospital
Director, Cardiac Rehabilitation, Barnes-Jewish West County Hospital

Contact Information:
Clinical Sciences Research Building, Room 3308
Phone: 314-362-8311
Fax: 314-361-8706
Email: BoineauJ@wudosis.wustl.edu, jpboineau@sbcglobal.net

Education and Training:
1955 University of South Carolina, Columbia, SC
1959 MD, Duke University School of Medicine, Durham, NC
1959-61 Intern and resident, Medicine, Georgetown University Hospital, Washington DC
1963-65 Fellow, Cardiovascular Disease, adult and pediatric, Duke University School of Medicine, Durham, NC
Board Certification: Diplomat of the American Board of Internal Medicine 1966

Military Service:
1961-63 Captain, USAFMC, and Consultant Cardiologist, USAF Hospital, Maxwell Air Force Base, Alabama

Academic Positions:
1965-72 Department of Medicine and Pediatrics, Duke University School of Medicine
1972-75 Department of Medicine, University of Southern California, Los Angeles, CA
1975-1984 Professor of Medicine and Pediatrics, Medicine College of Georgia, Augusta, GA
1984-Present Professor of Surgery and Medicine (Cardiovascular Division), Washington University School of Medicine, St. Louis, MO
1984-2004 Director, Dept. of Medicine Pacemaker Center and Out-patient Pacemaker Services, Washington University School of Medicine
1985-l998 Director, Clinical Sciences Research Building Surgical Research Facility, Washington University School of Medicine
1997-Present Professor of Biomedical Engineering, Washington University School of Medicine

Clinical Expertise:
Heart disease, myocardial infarction, pacemakers, atrial fibrillation and other arrhythmias, electrocardiography, cardiac rehabilitation

Research Interests:
Surgical treatment of cardiac arrhythmias
Atrial pacemaker complex
Basic anatomic and electrophysiologic mechanisms for arrhythmias and the abnormal electrocardiogram

Selected Publications:
Boineau JP, Farlow JW. Influence of probability (chance) on the exact timing of sudden death due to ventricular fibrillation: Why on Tuesday but not on Monday. In press.

Boineau JP. The early repolarization variant—normal or a marker of heart disease in certain subjects. J Electrocardiol 2007;40(1):3.e11-6.

Boineau JP. The early repolarization variant—an electrocardiographic enigma with both QRS and J-STT anomalies. J Electrocardiol 2007;40(1):3.e1-10.

Boineau JP. The ECG in multiple myocardial infarction and the progression of ischemic heart disease. Cardiorhythms, Inc., St. Louis, MO, 2005.

Byrd GD, Prasad SM, Ripplinger CM, Cassilly TR, Schuessler RB, Boineau JP, Damiano Jr: Importance of geometry and refractory period in sustaining atrial fibrillation. Circulation 2005; 112(9 Suppl):I7-13.

Wu J, Schuessler RB, Rodefeld MD, Saffitz JE, Boineau JP: Morphological and membrane characteristics of spider and spindle cells isolated from rabbit sinus node. Am J Physiol Heart Circ Physiol 2001; 280:H1232-H1240.

Nitta T, Lee R, Schuessler RB, Boineau JP, Cox JL: Radial approach: A new concept in surgical treatment for atrial fibrillation. I. Concept, anatomic and physiologic bases and development of a procedure. Ann Thorac Surg 1999; 67:27-35.

Nitta, T, Schuessler RB, Mitsuno M, Rokkas CK, Isobe F, Cronin CS, Cox JL, Boineau JP: Return cycle mapping after entrainment of ventricular tachycardia. Circulation 1998; 97:1164-1175.

Kwong KF, Schuessler RB, Green KG, Laing JG, Beyer EC, Boineau JP, Saffitz JE: Differential expression of gap junction proteins in the canine sinus node. Circ Res 1998; 82(5):604-612.

Kim K-B, Rodefeld MD, Schuessler RB, Cox JL, Boineau JP: Relationship between local atrial fibrillation interval and refractory period in the isolated canine atrium. Circulation 1996;94:2961-2967.

Cox JL, Jaquiss RDB, Boineau JP: Modification of the Maze procedure for atrial flutter and atrial fibrillation. II. Surgical technique of the Maze III procedure. J Thorac Cardiovasc Surg 1995;110:485-495.

Beau SL, Hand DE, Schuessler RB, Bromberg BI, Kwon B, Boineau JP, Saffitz JE: Relative densities of muscarinic cholinergic and β-adrenergic receptors in the canine sinoatrial node and their relation to sites of pacemaker activity. Circ Res 1995;77:957-963

Cox JL, Boineau JP, Schuessler RB, Kater KM, Lappas DG: Five-year experience with the Maze procedure for atrial fibrillation. Ann Thorac Surg 1993;56:814-824.

Schuessler RB, Kawamoto T, Hand DE, Mitsuno M, Bromberg BI, Cox JL, Boineau JP: Simultaneous epicardial and endocardial activation sequence mapping in the isolated canine right atrium. Circulation 1993;88:250-263.

Cox JL, Schuessler RB, D'Agostino HJ Jr, Stone CM, Chang BC, Cain ME, Corr PB, Boineau JP: The surgical treatment of atrial fibrillation: III. Development of a definitive surgical procedure. J Thorac Cardiovasc Surg 1991;101:569-583.

Cox JL, Schuessler RB, Boineau JP: Surgery for atrial fibrillation. Cardiac Arrhythmia Surgery: State of the Art Reviews 1990;4:207-218.

Stone CM, Chang BC, Tweddell JS, Sato S, Schuessler RB, Barzilai B, Boineau JP, Cox JL: Ablation of atrial fibrillation by the Maze Procedure. Surgical Forum 1989;40:213-215.

Harada A, D'Agostino HJ Jr, Schuessler RB, Boineau JP, Cox JL: Potential distribution mapping: new method for precise localization of intramural septal origin of ventricular tachycardia. Circulation 1988;78 (Supp. III):III-137--III-147.

Boineau JP, Canavan TE, Schuessler RB, Cain ME, Corr PB, Cox JL: Demonstration of a widely distributed atrial pacemaker complex in the human heart. Circulation 1988;77:1221-1237.

D'Agostino HJ Jr, Harada A, Eisenberg SB, Schuessler RB, Boineau JP, Cox JL: Surgical ablation of atrial fibrillation in a canine model of chronic mitral regurgitation. Surgical Forum 1986;37:302-303.

Boineau JP, Miller CB, Schuessler RB, Roeske WR, Autry LJ, Wylds AC, Hill DA: Activation sequence and potential distribution maps demonstrating multicentric atrial impulse origin in dogs. Circ Res 1984;54:332-347.

Boineau JP, Schuessler RB, Hackel DB, Miller CB, Brockus CW, Wylds AC: Widespread distribution and rate differentiation of the atrial pacemaker complex. Am J Physiol 1980;239 (Heart Circ Physiol 8):H406-H415.

Boineau JP, Schuessler RB, Mooney CR, Miller CB, Wylds AC, Hudson RD, Borremans JM, Brockus CW: Natural and evoked atrial flutter due to circus movement in dogs. Am J Cardiol 1980;45:1167-1181

Boineau JP, Schuessler RB, Mooney CR, Wylds AC, Miller CB, Hudson RD, Borremans JM, Brockus CW: Multicentric origin of the atrial depolarization wave: The pacemaker complex. Circulation 1978;58:1036-1048.

Wittig JH, Boineau JP: Surgical treatment of ventricular arrhythmias using epicardial, transmural, and endocardial mapping. Ann Thorac Surg 1975;20:117-126.

Boineau JP, Moore EN, Sealy WC, Kasell JH: Epicardial mapping in Wolff-Parkinson-White syndrome. Arch Intern Med 1975;135:422-431.

Boineau JP, Cox JL: Slow ventricular activation in acute myocardial infarction. A source of re-entrant premature ventricular contractions. Circulation 1973;48:702-713.

Boineau JP, Moore EN, Patterson DF: Relationship between the ECG, ventricular activation, and the ventricular conduction system in ostium primum ASD. Circulation 1973;48:556-564.

Boineau JP, Moore EN: Evidence for propagation of activation across an accessory atrioventricular connection in types A and B pre-excitation. Circulation 1970;41:375-397.

Boineau JP, Hill JD, Spach MS, Moore EN: Basis of the electrocardiogram in right ventricular hypertrophy. Am Heart J 1968;76:605-627.

Boineau JP, Spach MS, Ayers CR: Genesis of the electrocardiogram in atrial septal defect. Am Heart J 1964;68:637-651.


· About the Division · Clinical Programs · Research Activities · Educational Programs · Centers of Excellence · Faculty Faculty Login · Links · Contact Us · Donors	John P. Boineau, MD Professor of Surgery, Medicine, and Biomedical Engineering Co-Director, Cardiothoracic Surgery Research Laboratory Co-Director, Nuclear Stress Lab, Barnes-Jewish Hospital Director, Cardiac Rehabilitation, Barnes-Jewish West County Hospital Contact Information: Clinical Sciences Research Building, Room 3308 Phone: 314-362-8311 Fax: 314-361-8706 Email: BoineauJ@wudosis.wustl.edu, jpboineau@sbcglobal.net Education and Training: 1955 University of South Carolina, Columbia, SC 1959 MD, Duke University School of Medicine, Durham, NC 1959-61 Intern and resident, Medicine, Georgetown University Hospital, Washington DC 1963-65 Fellow, Cardiovascular Disease, adult and pediatric, Duke University School of Medicine, Durham, NC Board Certification: Diplomat of the American Board of Internal Medicine 1966 Military Service: 1961-63 Captain, USAFMC, and Consultant Cardiologist, USAF Hospital, Maxwell Air Force Base, Alabama Academic Positions: 1965-72 Department of Medicine and Pediatrics, Duke University School of Medicine 1972-75 Department of Medicine, University of Southern California, Los Angeles, CA 1975-1984 Professor of Medicine and Pediatrics, Medicine College of Georgia, Augusta, GA 1984-Present Professor of Surgery and Medicine (Cardiovascular Division), Washington University School of Medicine, St. Louis, MO 1984-2004 Director, Dept. of Medicine Pacemaker Center and Out-patient Pacemaker Services, Washington University School of Medicine 1985-l998 Director, Clinical Sciences Research Building Surgical Research Facility, Washington University School of Medicine 1997-Present Professor of Biomedical Engineering, Washington University School of Medicine Clinical Expertise: Heart disease, myocardial infarction, pacemakers, atrial fibrillation and other arrhythmias, electrocardiography, cardiac rehabilitation Research Interests: Surgical treatment of cardiac arrhythmias Atrial pacemaker complex Basic anatomic and electrophysiologic mechanisms for arrhythmias and the abnormal electrocardiogram Selected Publications: Boineau JP, Farlow JW. Influence of probability (chance) on the exact timing of sudden death due to ventricular fibrillation: Why on Tuesday but not on Monday. In press. Boineau JP. The early repolarization variant—normal or a marker of heart disease in certain subjects. J Electrocardiol 2007;40(1):3.e11-6. Boineau JP. The early repolarization variant—an electrocardiographic enigma with both QRS and J-STT anomalies. J Electrocardiol 2007;40(1):3.e1-10. Boineau JP. The ECG in multiple myocardial infarction and the progression of ischemic heart disease. Cardiorhythms, Inc., St. Louis, MO, 2005. Byrd GD, Prasad SM, Ripplinger CM, Cassilly TR, Schuessler RB, Boineau JP, Damiano Jr: Importance of geometry and refractory period in sustaining atrial fibrillation. Circulation 2005; 112(9 Suppl):I7-13. Wu J, Schuessler RB, Rodefeld MD, Saffitz JE, Boineau JP: Morphological and membrane characteristics of spider and spindle cells isolated from rabbit sinus node. Am J Physiol Heart Circ Physiol 2001; 280:H1232-H1240. Nitta T, Lee R, Schuessler RB, Boineau JP, Cox JL: Radial approach: A new concept in surgical treatment for atrial fibrillation. I. Concept, anatomic and physiologic bases and development of a procedure. Ann Thorac Surg 1999; 67:27-35. Nitta, T, Schuessler RB, Mitsuno M, Rokkas CK, Isobe F, Cronin CS, Cox JL, Boineau JP: Return cycle mapping after entrainment of ventricular tachycardia. Circulation 1998; 97:1164-1175. Kwong KF, Schuessler RB, Green KG, Laing JG, Beyer EC, Boineau JP, Saffitz JE: Differential expression of gap junction proteins in the canine sinus node. Circ Res 1998; 82(5):604-612. Kim K-B, Rodefeld MD, Schuessler RB, Cox JL, Boineau JP: Relationship between local atrial fibrillation interval and refractory period in the isolated canine atrium. Circulation 1996;94:2961-2967. Cox JL, Jaquiss RDB, Boineau JP: Modification of the Maze procedure for atrial flutter and atrial fibrillation. II. Surgical technique of the Maze III procedure. J Thorac Cardiovasc Surg 1995;110:485-495. Beau SL, Hand DE, Schuessler RB, Bromberg BI, Kwon B, Boineau JP, Saffitz JE: Relative densities of muscarinic cholinergic and β-adrenergic receptors in the canine sinoatrial node and their relation to sites of pacemaker activity. Circ Res 1995;77:957-963 Cox JL, Boineau JP, Schuessler RB, Kater KM, Lappas DG: Five-year experience with the Maze procedure for atrial fibrillation. Ann Thorac Surg 1993;56:814-824. Schuessler RB, Kawamoto T, Hand DE, Mitsuno M, Bromberg BI, Cox JL, Boineau JP: Simultaneous epicardial and endocardial activation sequence mapping in the isolated canine right atrium. Circulation 1993;88:250-263. Cox JL, Schuessler RB, D'Agostino HJ Jr, Stone CM, Chang BC, Cain ME, Corr PB, Boineau JP: The surgical treatment of atrial fibrillation: III. Development of a definitive surgical procedure. J Thorac Cardiovasc Surg 1991;101:569-583. Cox JL, Schuessler RB, Boineau JP: Surgery for atrial fibrillation. Cardiac Arrhythmia Surgery: State of the Art Reviews 1990;4:207-218. Stone CM, Chang BC, Tweddell JS, Sato S, Schuessler RB, Barzilai B, Boineau JP, Cox JL: Ablation of atrial fibrillation by the Maze Procedure. Surgical Forum 1989;40:213-215. Harada A, D'Agostino HJ Jr, Schuessler RB, Boineau JP, Cox JL: Potential distribution mapping: new method for precise localization of intramural septal origin of ventricular tachycardia. Circulation 1988;78 (Supp. III):III-137--III-147. Boineau JP, Canavan TE, Schuessler RB, Cain ME, Corr PB, Cox JL: Demonstration of a widely distributed atrial pacemaker complex in the human heart. Circulation 1988;77:1221-1237. D'Agostino HJ Jr, Harada A, Eisenberg SB, Schuessler RB, Boineau JP, Cox JL: Surgical ablation of atrial fibrillation in a canine model of chronic mitral regurgitation. Surgical Forum 1986;37:302-303. Boineau JP, Miller CB, Schuessler RB, Roeske WR, Autry LJ, Wylds AC, Hill DA: Activation sequence and potential distribution maps demonstrating multicentric atrial impulse origin in dogs. Circ Res 1984;54:332-347. Boineau JP, Schuessler RB, Hackel DB, Miller CB, Brockus CW, Wylds AC: Widespread distribution and rate differentiation of the atrial pacemaker complex. Am J Physiol 1980;239 (Heart Circ Physiol 8):H406-H415. Boineau JP, Schuessler RB, Mooney CR, Miller CB, Wylds AC, Hudson RD, Borremans JM, Brockus CW: Natural and evoked atrial flutter due to circus movement in dogs. Am J Cardiol 1980;45:1167-1181 Boineau JP, Schuessler RB, Mooney CR, Wylds AC, Miller CB, Hudson RD, Borremans JM, Brockus CW: Multicentric origin of the atrial depolarization wave: The pacemaker complex. Circulation 1978;58:1036-1048. Wittig JH, Boineau JP: Surgical treatment of ventricular arrhythmias using epicardial, transmural, and endocardial mapping. Ann Thorac Surg 1975;20:117-126. Boineau JP, Moore EN, Sealy WC, Kasell JH: Epicardial mapping in Wolff-Parkinson-White syndrome. Arch Intern Med 1975;135:422-431. Boineau JP, Cox JL: Slow ventricular activation in acute myocardial infarction. A source of re-entrant premature ventricular contractions. Circulation 1973;48:702-713. Boineau JP, Moore EN, Patterson DF: Relationship between the ECG, ventricular activation, and the ventricular conduction system in ostium primum ASD. Circulation 1973;48:556-564. Boineau JP, Moore EN: Evidence for propagation of activation across an accessory atrioventricular connection in types A and B pre-excitation. Circulation 1970;41:375-397. Boineau JP, Hill JD, Spach MS, Moore EN: Basis of the electrocardiogram in right ventricular hypertrophy. Am Heart J 1968;76:605-627. Boineau JP, Spach MS, Ayers CR: Genesis of the electrocardiogram in atrial septal defect. Am Heart J 1964;68:637-651.